Senior Scientist (T Cell Engineering)

Biopolis Rd, Singapore
Description

We are looking for a Senior Scientist (T Cell Engineering) to join our R&D team as we expand our drug developmental program. Reporting to the VP of Research, the candidate will contribute to the translational pipeline by developing methodologies and workflows for various immune-based therapeutic modalities, and validating drug candidates. The successful candidate will have excellent technical competencies, analytical and strategic thinking abilities, and is able to work effectively across multiple projects.

Responsibilities
  • Independently establish SOPs to enable primary T cell engineering using delivery methods including the use of viral and non-viral approaches such as, but not limiting to, lentiviral transduction and transfection using electroporation methods.

  • Develop and execute small to large scale production of engineered cells for in vitro and in vivo uses.

  • Develop and execute various in vitro and/or in vivo cell-based functional assays to validate developmental candidates.

  • Perform data analysis of experimental results and present work regularly to various stakeholders.

  • Work with other R&D team members to improve pipeline workflow and technology development.

  • Contribute to scientific and strategy discussions to achieve R&D milestones.

  • Contribute to patents, publications, and technical reports.

Requirements
  • PhD in Life Science, Biotechnology or related Biological Sciences disciplines (3 years of post-doc or industry experience). Industry experience is highly advantageous.

  • Experienced in culture of immune cells for genetic modification and familiarity with development of cell based immunotherapies

  • Ability to design vector systems for CAR-T/ TCR-T expression

  • Ability to work independently and with other team members

  • Able to adapt to a fast paced start-up environment


Interested applicants are invited to apply with their CV and cover letter to careers@pairxbio.com.


We thank all applicants for their interest, however, only those selected will be invited for an interview.